FOXD3
Information FOXD3
- Description
Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis. {ECO:0000269|PubMed:12381664, ECO:0000269|PubMed:8798505}.
- Full Name
forkhead box D3
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 8
- Biotypes
- 2
- Peaks
- 22,536
- Non-redundant peaks
- 15,594
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 15221
- Official Gene Name
- Foxd3
- JASPAR
- MGI
- MGI:1347473
- Ensembl
- ENSMUSG00000067261
- UniProt
- Q61060
- Genevisible
- Q61060
- RefSeq
- NM_010425
- Aliases
- CWH3; Genesis; Hfh2
Datasets Table for FOXD3
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| FOXD3 | mESC | E2 | GEO | Mus musculus | GSE58407 | 225 | ||
| FOXD3 | mESC | CKO | GEO | Mus musculus | GSE58407 | 1,609 | ||
| FOXD3 | mESC | HA | GEO | Mus musculus | GSE70545 | 9,147 | ||
| FOXD3 | mESC | R-cell | GEO | Mus musculus | GSE58407 | 168 | ||
| FOXD3 | EpiLC | dY-cell | GEO | Mus musculus | GSE58407 | 48,001 | ||
| FOXD3 | EpiLC | E2 | GEO | Mus musculus | GSE58407 | 534 | ||
| FOXD3 | EpiLC | CKO | GEO | Mus musculus | GSE58407 | 707 | ||
| FOXD3 | mESC | FLAG | GEO | Mus musculus | GSE70545 | 9,931 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |