FUS

Information FUS

Description

This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009]

Full Name

FUS RNA binding protein

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
4
Biotypes
2
Peaks
30,384
Non-redundant peaks
14,402

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
2521
Official Gene Name
FUS
JASPAR
Ensembl
ENSG00000089280
UniProt
P35637
Genevisible
P35637
RefSeq
NM_001170634
Aliases
ALS6; ETM4; FUS1; HNRNPP2; POMP75; TLS; hnRNP-P2
All peaks FUS
Download BED file
Non redundant peaks FUS
Download BED file
SEQUENCES FUS
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for FUS

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
FUS Hep-G2 GEO Homo sapiens GSE120104 11,229
FUS K-562 GEO Homo sapiens GSE120104 2,740
FUS K-562 ENCODE Homo sapiens ENCSR051DXE 4,921
FUS Hep-G2 ENCODE Homo sapiens ENCSR590QQP 11,494
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks