GFI1B

Information GFI1B

Description

This gene encodes a zinc-finger containing transcriptional regulator that is primarily expressed in cells of hematopoietic lineage. The encoded protein complexes with numerous other transcriptional regulatory proteins including GATA-1, runt-related transcription factor 1 and histone deacetylases to control expression of genes involved in the development and maturation of erythrocytes and megakaryocytes. Mutations in this gene are the cause of the autosomal dominant platelet disorder, platelet-type bleeding disorder-17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]

Full Name

growth factor independent 1B transcriptional repressor

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
10
Biotypes
5
Peaks
109,502
Non-redundant peaks
82,844

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
8328
Official Gene Name
GFI1B
JASPAR
Ensembl
ENSG00000165702
UniProt
Q5VTD9
Genevisible
Q5VTD9
RefSeq
NM_001135031
Aliases
BDPLT17; ZNF163B
All peaks GFI1B
Download BED file
Non redundant peaks GFI1B
Download BED file
SEQUENCES GFI1B
Download FASTA file
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Datasets Table for GFI1B

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
GFI1B CD34 GEO Homo sapiens GSE52924 3,589
GFI1B SET-2 insR GEO Homo sapiens GSE121424 659
GFI1B SET-2 GEO Homo sapiens GSE121424 4,249
GFI1B SET-2 GSK_insR GEO Homo sapiens GSE121424 862
GFI1B SET-2 GSK GEO Homo sapiens GSE121424 2,296
GFI1B K-562 GEO Homo sapiens GSE117944 9,084
GFI1B K-562 Wnt GEO Homo sapiens GSE117944 10,711
GFI1B K-562 ENCODE Homo sapiens ENCSR509GDT 69,189
GFI1B HEK293 ENCODE Homo sapiens ENCSR445PDR 8,698
GFI1B dermal-fibroblast GEO Homo sapiens GSE51025 165
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks