GLI2
Information GLI2
- Description
Functions as transcription regulator in the hedgehog (Hh) pathway (PubMed:9006072). Functions as transcriptional activator (PubMed:10806483). May also function as transcriptional repressor (PubMed:10433919). Requires STK36 for full transcriptional activator activity (PubMed:10806483). Binds to the DNA sequence 5'-GAACCACCCA-3' which is part of the TRE-2S regulatory element (By similarity). Is involved in the smoothened (SHH) signaling pathway (PubMed:10433919). Required for normal skeleton development (PubMed:9006072). {ECO:0000250|UniProtKB:P10070, ECO:0000269|PubMed:10806483, ECO:0000269|PubMed:9006072, ECO:0000305|PubMed:10433919}.(Source UnitProtKB).
- Full Name
GLI-Kruppel family member GLI2
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 3
- Biotypes
- 3
- Peaks
- 13,636
- Non-redundant peaks
- 12,975
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 14633
- Official Gene Name
- Gli2
- JASPAR
- MGI
- MGI:95728
- Ensembl
- ENSMUSG00000048402
- UniProt
- Q0VGT2
- Genevisible
- Q0VGT2
- RefSeq
- NM_001081125
- Aliases
Datasets Table for GLI2
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| GLI2 | mESC | GEO | Mus musculus | GSE84760 | 6,270 | |||
| GLI2 | head | E10-5 | GEO | Mus musculus | GSE131165 | 4,606 | ||
| GLI2 | intestine | GEO | Mus musculus | GSE103690 | 2,760 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |