GLIS3
Information GLIS3
- Description
This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined. [provided by RefSeq, Jul 2008]
- Full Name
GLIS family zinc finger 3
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 2
- Biotypes
- 2
- Peaks
- 55,691
- Non-redundant peaks
- 55,260
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 169792
- Official Gene Name
- GLIS3
- JASPAR
- MA0737
- Ensembl
- ENSG00000107249
- UniProt
- Q8NEA6
- Genevisible
- Q8NEA6
- RefSeq
- NM_001042413
- Aliases
- MGC33662
Datasets Table for GLIS3
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| GLIS3 | SK-N-SH | all-trans-retinoic-acid_6-uM_48-hour | ENCODE | Homo sapiens | ENCSR507BWM | 4,881 | ||
| GLIS3 | H9 | plus | GEO | Homo sapiens | GSE109562 | 50,810 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |