HAND1
Information HAND1
- Description
Transcription factor that plays an essential role in both trophoblast giant cell differentiation and in cardiac morphogenesis (PubMed:9500551, PubMed:16759287). Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) (PubMed:7791788). Acts as a transcriptional repressor of SOX15 (PubMed:16759287). In the adult, could be required for ongoing expression of cardiac-specific genes (By similarity). {ECO:0000250|UniProtKB:O96004, ECO:0000269|PubMed:16759287, ECO:0000269|PubMed:7791788, ECO:0000269|PubMed:9500551}.(Source UnitProtKB).
- Full Name
heart and neural crest derivatives expressed 1
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 4,815
- Non-redundant peaks
- 4,815
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 15110
- Official Gene Name
- Hand1
- JASPAR
- MGI
- MGI:103577
- Ensembl
- ENSMUSG00000037335
- UniProt
- Q64279
- Genevisible
- Q64279
- RefSeq
- NM_008213
- Aliases
- Ehand1; Hxt; Th1; Thing1; bHLHa27; eHAND