HDAC1

Information HDAC1

Description

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]

Full Name

histone deacetylase 1

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
19
Biotypes
7
Peaks
425,642
Non-redundant peaks
187,560

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
3065
Official Gene Name
HDAC1
JASPAR
Ensembl
ENSG00000116478
UniProt
Q13547
Genevisible
Q13547
RefSeq
NM_004964
Aliases
GON-10; HD1; KDAC1; RPD3; RPD3L1
All peaks HDAC1
Download BED file
Non redundant peaks HDAC1
Download BED file
SEQUENCES HDAC1
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for HDAC1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
HDAC1 MCF-7 parental GEO Homo sapiens GSE123284 28,884
HDAC1 MCF-7 ARID1A-KO GEO Homo sapiens GSE123284 16,980
HDAC1 MCF-7 ARID1A-KO_clone14 GEO Homo sapiens GSE123284 20,046
HDAC1 MCF-7 parental_4-hydroxytamoxifen GEO Homo sapiens GSE123284 50,194
HDAC1 VCaP ETOH GEO Homo sapiens GSE28950 3,086
HDAC1 VCaP DHAT_2H GEO Homo sapiens GSE28950 4,021
HDAC1 PC-3 GDC-resist GEO Homo sapiens GSE147455 11,840
HDAC1 PC-3 GEO Homo sapiens GSE147455 23,764
HDAC1 Hep-G2 ENCODE Homo sapiens ENCSR750OWO 34,337
HDAC1 NB4 GEO Homo sapiens GSE126720 25,105
HDAC1 K-562 GEO Homo sapiens GSE140325 4,701
HDAC1 K-562 dilution-6-100 GEO Homo sapiens GSE140325 39,061
HDAC1 MCF-7 ARID1A-KO_4-OHT_clone14 GEO Homo sapiens GSE123284 22,384
HDAC1 K-562 ENCODE Homo sapiens ENCSR000AQF 21,178
HDAC1 K-562 ENCODE Homo sapiens ENCSR711VWL 55,890
HDAC1 K-562 ENCODE Homo sapiens ENCSR387UWP 58,800
HDAC1 K-562 ENCODE Homo sapiens ENCSR568PGX 806
HDAC1 AML GEO Homo sapiens GSE131939 3,261
HDAC1 AML shaml1-eto GEO Homo sapiens GSE131939 1,304
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks