HDAC2

Information HDAC2

Description

This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]

Full Name

histone deacetylase 2

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
21
Biotypes
10
Peaks
679,092
Non-redundant peaks
359,297

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
3066
Official Gene Name
HDAC2
JASPAR
Ensembl
ENSG00000196591
UniProt
Q92769
Genevisible
Q92769
RefSeq
NM_001527
Aliases
HD2; KDAC2; RPD3; YAF1
All peaks HDAC2
Download BED file
Non redundant peaks HDAC2
Download BED file
SEQUENCES HDAC2
Download FASTA file
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Datasets Table for HDAC2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
HDAC2 VCaP DHAT_2H GEO Homo sapiens GSE28950 10,120
HDAC2 VCaP ETOH GEO Homo sapiens GSE28950 12,947
HDAC2 PC-3 GEO Homo sapiens GSE147455 70,888
HDAC2 PC-3 GDC-resist GEO Homo sapiens GSE147455 38,827
HDAC2 RH4 DMSO-6H GEO Homo sapiens GSE116344 41,170
HDAC2 RH4 Entinostat-6H GEO Homo sapiens GSE116344 64,175
HDAC2 RH4 Entinostat-6H_bioMerck GEO Homo sapiens GSE116344 1,909
HDAC2 RH4 DMSO-6H_bioMerck GEO Homo sapiens GSE116344 10,910
HDAC2 K-562 GEO Homo sapiens GSE140325 31,675
HDAC2 WA01 ENCODE Homo sapiens ENCSR000BNR 13,735
HDAC2 WA01 ENCODE Homo sapiens ENCSR000AVB 56,027
HDAC2 MCF-7 ENCODE Homo sapiens ENCSR000BTP 49,037
HDAC2 K-562 ENCODE Homo sapiens ENCSR000BMG 21,812
HDAC2 K-562 ENCODE Homo sapiens ENCSR075HTM 58,783
HDAC2 K-562 ENCODE Homo sapiens ENCSR000AQG 14,940
HDAC2 K-562 ENCODE Homo sapiens ENCSR893WSB 74,329
HDAC2 Hep-G2 ENCODE Homo sapiens ENCSR000BMC 68,927
HDAC2 Hep-G2 ENCODE Homo sapiens ENCSR337NWW 5,311
HDAC2 A-549 ENCODE Homo sapiens ENCSR659LJJ 10,212
HDAC2 GM12878 ENCODE Homo sapiens ENCSR330OEO 7,926
HDAC2 pre-B-cell GEO Homo sapiens GSE107886 15,432
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks