HDAC4

Information HDAC4

Description

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Deacetylates HSPA1A and HSPA1A at 'Lys-77' leading to their preferential binding to co-chaperone STUB1. {ECO:0000250|UniProtKB:P56524}.(Source UnitProtKB).

Full Name

histone deacetylase 4

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
4,654
Non-redundant peaks
4,654

TF Classification

Familly
NA
Sub Familly
NA

Source JASPAR

External IDs

NCBI Gene
208727
Official Gene Name
Hdac4
JASPAR
MGI
MGI:3036234
Ensembl
ENSMUSG00000026313
UniProt
Q6NZM9
Genevisible
Q6NZM9
RefSeq
NM_207225
Aliases
4932408F19Rik
All peaks HDAC4
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Non redundant peaks HDAC4
Download BED file
SEQUENCES HDAC4
Download FASTA file
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Datasets Table for HDAC4

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
HDAC4 Th17 GEO Mus musculus GSE92531 4,654
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks