HDAC4
Information HDAC4
- Description
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Deacetylates HSPA1A and HSPA1A at 'Lys-77' leading to their preferential binding to co-chaperone STUB1. {ECO:0000250|UniProtKB:P56524}.(Source UnitProtKB).
- Full Name
histone deacetylase 4
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 4,654
- Non-redundant peaks
- 4,654
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 208727
- Official Gene Name
- Hdac4
- JASPAR
- MGI
- MGI:3036234
- Ensembl
- ENSMUSG00000026313
- UniProt
- Q6NZM9
- Genevisible
- Q6NZM9
- RefSeq
- NM_207225
- Aliases
- 4932408F19Rik