HDAC8
Information HDAC8
- Description
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
- Full Name
histone deacetylase 8
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 2
- Biotypes
- 1
- Peaks
- 33,024
- Non-redundant peaks
- 29,785
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 55869
- Official Gene Name
- HDAC8
- JASPAR
- Ensembl
- ENSG00000147099
- UniProt
- Q9BY41
- Genevisible
- Q9BY41
- RefSeq
- NM_001166418
- Aliases
- KDAC8
Datasets Table for HDAC8
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| HDAC8 | K-562 | ENCODE | Homo sapiens | ENCSR835TCD | 22,871 | |||
| HDAC8 | K-562 | ENCODE | Homo sapiens | ENCSR000DJZ | 10,153 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |