HIF1A
Information HIF1A
- Description
This gene encodes the alpha subunit which, along with the beta subunit, forms a heterodimeric transcription factor that regulates the cellular and developmental response to reduced oxygen tension. The transcription factor has been shown to regulate genes involved in several biological processes, including erythropoiesis and angiogenesis which aid in increased delivery of oxygen to hypoxic regions. The transcription factor also plays a role in the induction of genes involved in cell proliferation and survival, energy metabolism, apoptosis, and glucose and iron metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
- Full Name
hypoxia inducible factor 1, alpha subunit
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 2
- Biotypes
- 2
- Peaks
- 21,320
- Non-redundant peaks
- 21,127
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 15251
- Official Gene Name
- Hif1a
- JASPAR
- MGI
- MGI:106918
- Ensembl
- ENSMUSG00000021109
- UniProt
- Q61221
- Genevisible
- Q61221
- RefSeq
- NM_010431
- Aliases
- AA959795; HIF-1-alpha; HIF-1alpha; HIF1-alpha; HIF1alpha; MOP1; bHLHe78
Datasets Table for HIF1A
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| HIF1A | heart | embryo | GEO | Mus musculus | GSE61247 | 224 | ||
| HIF1A | Th17 | GEO | Mus musculus | GSE40918 | 21,096 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |