HMGB2
Information HMGB2
- Description
This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. [provided by RefSeq, Jul 2008]
- Full Name
high mobility group box 2
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 3
- Biotypes
- 2
- Peaks
- 25,093
- Non-redundant peaks
- 23,158
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 3148
- Official Gene Name
- HMGB2
- JASPAR
- Ensembl
- ENSG00000164104
- UniProt
- P26583
- Genevisible
- P26583
- RefSeq
- NM_001130688
- Aliases
- HMG2
Datasets Table for HMGB2
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| HMGB2 | IMR-90 | senescent | GEO | Homo sapiens | GSE98245 | 782 | ||
| HMGB2 | IMR-90 | proliferating | GEO | Homo sapiens | GSE98245 | 6,768 | ||
| HMGB2 | HUVEC-C | GEO | Homo sapiens | GSE98245 | 17,543 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |