HNF4A
Information HNF4A
- Description
The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012]
- Full Name
hepatocyte nuclear factor 4 alpha
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 20
- Biotypes
- 11
- Peaks
- 572,696
- Non-redundant peaks
- 232,794
TF Classification
- Super Class
- Zinc-coordinating DNA-binding domains
- Class
- Nuclear receptors with C4 zinc fingers
- Familly
- RXR-related receptors (NR2)
- Sub Familly
- HNF-4 (NR2A)
Source TFClass
Datasets Table for HNF4A
Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
---|---|---|---|---|---|---|---|---|
HNF4A | HCCLM3 | High-Glucose | GEO | Homo sapiens | GSE101553 | 2,509 | ||
HNF4A | HCCLM3 | Low-Glucose | GEO | Homo sapiens | GSE101553 | 1,240 | ||
HNF4A | LoVo | PHASES | GEO | Homo sapiens | GSE51290 | 11,657 | ||
HNF4A | LoVo | PHASEM | GEO | Homo sapiens | GSE51290 | 1,507 | ||
HNF4A | IM95 | GEO | Homo sapiens | GSE114018 | 59,587 | |||
HNF4A | GP5D | SIRAD21 | GEO | Homo sapiens | GSE51234 | 4,148 | ||
HNF4A | GP5D | GEO | Homo sapiens | GSE51234 | 14,879 | |||
HNF4A | Hep-G2 | ENCODE | Homo sapiens | ENCSR469FBY | 73,059 | |||
HNF4A | Hep-G2 | ENCODE | Homo sapiens | ENCSR000BLF | 62,630 | |||
HNF4A | Hep-G2 | ENA | Homo sapiens | ERP000209 | 39,187 | |||
Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
Showing 1 to 10 of 20 entries