HOXB8

Information HOXB8

Description

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania. [provided by RefSeq, Jul 2008]

Full Name

homeobox B8

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
3
Biotypes
3
Peaks
92,854
Non-redundant peaks
81,045

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
3218
Official Gene Name
HOXB8
JASPAR
Ensembl
ENSG00000120068
UniProt
P17481
Genevisible
P17481
RefSeq
NM_024016
Aliases
HOX2; HOX2D; Hox-2.4
All peaks HOXB8
Download BED file
Non redundant peaks HOXB8
Download BED file
SEQUENCES HOXB8
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for HOXB8

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
HOXB8 CFPAC-1 HOXB8-OE GEO Homo sapiens GSE119930 58,810
HOXB8 PANC-1 GEO Homo sapiens GSE119930 23,729
HOXB8 K-562 GEO Homo sapiens GSE121208 10,315
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks