HOXB8
Information HOXB8
- Description
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania. [provided by RefSeq, Jul 2008]
- Full Name
homeobox B8
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 3
- Biotypes
- 3
- Peaks
- 92,854
- Non-redundant peaks
- 81,045
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
Datasets Table for HOXB8
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| HOXB8 | CFPAC-1 | HOXB8-OE | GEO | Homo sapiens | GSE119930 | 58,810 | ||
| HOXB8 | PANC-1 | GEO | Homo sapiens | GSE119930 | 23,729 | |||
| HOXB8 | K-562 | GEO | Homo sapiens | GSE121208 | 10,315 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |