Hand

The gene Hand is referred to in FlyBase by the symbol DmelHand (CG18144, FBgn0032209). It is a protein_coding_gene from Dmel. It has one annotated transcript and one polypeptide. Gene sequence location is 2L:10292679..10295385. Its molecular function is described by: protein dimerization activity; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific. It is involved in the biological process described with 9 unique terms, many of which group under: cell morphogenesis involved in neuron differentiation; post-embryonic animal organ development; hematopoietic or lymphoid organ development; apoptotic process; negative regulation of biological process. 16 alleles are reported. The phenotypes of these alleles manifest in: pericardial cell; embryonic/larval heart; excretory system; primordium; segmental subdivision of integument. The phenotypic classes of alleles include: increased mortality during development; phenotype; lethal; some die during larval stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 06-24 hour embryonic stages, during early pupal stages.

hand

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6