Hnf4

The gene Hepatocyte nuclear factor 4 is referred to in FlyBase by the symbol DmelHnf4 (CG9310, FBgn0004914). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (4 unique). Gene sequence location is 2L:8687226..8709611. Its molecular function is described by: zinc ion binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; steroid hormone receptor activity; nuclear receptor activity. It is involved in the biological process described with 8 unique terms, many of which group under: primary metabolic process; developmental process; lipid metabolic process; regulation of biological quality; organic substance catabolic process. 47 alleles are reported. The phenotypes of these alleles manifest in: intracellular anatomical structure; intracellular organelle; intracellular membrane-bounded organelle; organelle; cell. The phenotypic classes of alleles include: increased mortality during development; increased mortality; fertile; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 and 18-24 hour embryonic stages, in stages of adults of both sexes.

Hepatocyte nuclear factor 4

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6