Hsf

The gene Heat shock factor is referred to in FlyBase by the symbol DmelHsf (CG5748, FBgn0001222). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 2R:18130303..18134634. Its molecular function is described by: RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein binding; DNA-binding transcription factor activity; DNA binding; sequence-specific DNA binding. It is involved in the biological process described with 8 unique terms, many of which group under: response to stress; response to stimulus; response to other organism; negative regulation of nucleic acid-templated transcription; response to temperature stimulus. 28 alleles are reported. The phenotypes of these alleles manifest in: egg chamber; salivary gland; nurse cell; ganglion mother cell; polytene chromosome. The phenotypic classes of alleles include: stress response defective; increased mortality during development; phenotype; lethal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late pupal stages, in adult female stages.

Heat shock factor

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6