IKZF3
Information IKZF3
- Description
Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Binds to GGGAA. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner. {ECO:0000269|PubMed:9155026, ECO:0000269|PubMed:9806640}.(Source UnitProtKB).
- Full Name
IKAROS family zinc finger 3
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 3,788
- Non-redundant peaks
- 3,788
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 22780
- Official Gene Name
- Ikzf3
- JASPAR
- MGI
- MGI:1342542
- Ensembl
- ENSMUSG00000018168
- UniProt
- O08900
- Genevisible
- O08900
- RefSeq
- NM_011771
- Aliases
- 5830411O07Rik; Aiolos; Zfpn1a3; Znfn1a3