IKZF3
Information IKZF3
- Description
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]
- Full Name
IKAROS family zinc finger 3
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 2
- Biotypes
- 2
- Peaks
- 96,741
- Non-redundant peaks
- 86,738
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 22806
- Official Gene Name
- IKZF3
- JASPAR
- Ensembl
- ENSG00000161405
- UniProt
- Q9UKT9
- Genevisible
- Q9UKT9
- RefSeq
- NM_001257408
- Aliases
- AIO; AIOLOS; ZNFN1A3
Datasets Table for IKZF3
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| IKZF3 | HEK293 | ENCODE | Homo sapiens | ENCSR304AMN | 46,324 | |||
| IKZF3 | pre-B-cell | GEO | Homo sapiens | GSE107886 | 50,417 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |