IKZF
Information IKZF
- Description
Targets IKFZ porteins. DNA-binding protein Ikaros. Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Binds with higher affinity to gamma satellite A. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells (By similarity). (Source UniProtKB)
- Full Name
IKZF
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 5
- Biotypes
- 3
- Peaks
- 79,701
- Non-redundant peaks
- 53,716
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
Datasets Table for IKZF
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| IKZF | pre-B-cell | GEO | Mus musculus | GSE38169 | 29,802 | |||
| IKZF | pre-B-cell | HA | GEO | Mus musculus | GSE38169 | 11,707 | ||
| IKZF | T29-33 | GEO | Mus musculus | GSE46119 | 2,560 | |||
| IKZF | liver | pre-pro-B-cell | GEO | Mus musculus | GSE66978 | 4,266 | ||
| IKZF | liver | pro-B-cell | GEO | Mus musculus | GSE66978 | 31,366 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |