ILF3

Information ILF3

Description

This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2014]

Full Name

interleukin enhancer binding factor 3

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
2
Biotypes
1
Peaks
54,986
Non-redundant peaks
53,284

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
3609
Official Gene Name
ILF3
JASPAR
Ensembl
ENSG00000129351
UniProt
Q12906
Genevisible
Q12906
RefSeq
NM_001137673
Aliases
CBTF; DRBF; DRBP76; MMP4; MPHOSPH4; MPP4; MPP4110; NF-AT-90; NF110; NF110b; NF90; NF90a; NF90b; NF90c; NF90ctv; NFAR; NFAR-1; NFAR-2; NFAR110; NFAR2; NFAR90; TCP110; TCP80
All peaks ILF3
Download BED file
Non redundant peaks ILF3
Download BED file
SEQUENCES ILF3
Download FASTA file
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Datasets Table for ILF3

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
ILF3 K-562 GEO Homo sapiens GSE103215 52,414
ILF3 K-562 ENCODE Homo sapiens ENCSR632TJQ 2,572
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks