IRF2
Information IRF2
- Description
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.(Source UnitProtKB).
- Full Name
interferon regulatory factor 2
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 6
- Biotypes
- 4
- Peaks
- 23,727
- Non-redundant peaks
- 20,388
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
Datasets Table for IRF2
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| IRF2 | CRC | GEO | Mus musculus | GSE110175 | 5,743 | |||
| IRF2 | MEF | Hcfc2-KO | GEO | Mus musculus | GSE100436 | 2,795 | ||
| IRF2 | MEF | GEO | Mus musculus | GSE100436 | 4,212 | |||
| IRF2 | BMDC | GEO | Mus musculus | GSE36099 | 160 | |||
| IRF2 | TSC | GEO | Mus musculus | GSE110950 | 205 | |||
| IRF2 | TSC | differentiated | GEO | Mus musculus | GSE110950 | 10,612 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |