IRF8
Information IRF8
- Description
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq, Jul 2008]
- Full Name
interferon regulatory factor 8
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 13,867
- Non-redundant peaks
- 13,867
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 3394
- Official Gene Name
- IRF8
- JASPAR
- MA0652
- Ensembl
- ENSG00000140968
- UniProt
- Q02556
- Genevisible
- Q02556
- RefSeq
- NM_001363907
- Aliases
- H-ICSBP; ICSBP; ICSBP1; IMD32A; IMD32B; IRF-8