JMJD1C
Information JMJD1C
- Description
The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factors. It plays a role in the DNA-damage response pathway by demethylating the mediator of DNA damage checkpoint 1 (MDC1) protein, and is required for the survival of acute myeloid leukemia. Mutations in this gene are associated with Rett syndrome and intellectual disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
- Full Name
jumonji domain containing 1C
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 4
- Biotypes
- 4
- Peaks
- 218,143
- Non-redundant peaks
- 132,334
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 221037
- Official Gene Name
- JMJD1C
- JASPAR
- Ensembl
- ENSG00000171988
- UniProt
- Q15652
- Genevisible
- Q15652
- RefSeq
- NM_001282948
- Aliases
- DKFZp761F0118; FLJ14374; KDM3C; KIAA1380
Datasets Table for JMJD1C
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| JMJD1C | THP-1 | GEO | Homo sapiens | GSE63484 | 40,485 | |||
| JMJD1C | HL-60 | GEO | Homo sapiens | GSE63484 | 79,403 | |||
| JMJD1C | Kasumi-1 | GEO | Homo sapiens | GSE63484 | 45,445 | |||
| JMJD1C | NB4 | GEO | Homo sapiens | GSE63484 | 52,810 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |