KDM4C
Information KDM4C
- Description
Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. {ECO:0000250|UniProtKB:Q9H3R0}.(Source UnitProtKB).
- Full Name
lysine (K)-specific demethylase 4C
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 8
- Biotypes
- 4
- Peaks
- 258,173
- Non-redundant peaks
- 144,673
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 76804
- Official Gene Name
- Kdm4c
- JASPAR
- MGI
- MGI:1924054
- Ensembl
- ENSMUSG00000028397
- UniProt
- Q8VCD7
- Genevisible
- Q8VCD7
- RefSeq
- NM_144787
- Aliases
- 2410141F18Rik; Jmjd2c
Datasets Table for KDM4C
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| KDM4C | mESC | OHT | GEO | Mus musculus | GSE53936 | 561 | ||
| KDM4C | mESC | GEO | Mus musculus | GSE53936 | 30,333 | |||
| KDM4C | mESC | GEO | Mus musculus | GSE43229 | 61,608 | |||
| KDM4C | mESC-E14 | 2i | GEO | Mus musculus | GSE93721 | 23,100 | ||
| KDM4C | mESC-E14 | GEO | Mus musculus | GSE93721 | 53,961 | |||
| KDM4C | MLL-AF9 | OHT | GEO | Mus musculus | GSE81299 | 45,832 | ||
| KDM4C | MEF | GEO | Mus musculus | GSE53939 | 11,183 | |||
| KDM4C | MLL-AF9 | ctrl | GEO | Mus musculus | GSE81299 | 41,544 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |