KDM4C

Information KDM4C

Description

Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. {ECO:0000250|UniProtKB:Q9H3R0}.(Source UnitProtKB).

Full Name

lysine (K)-specific demethylase 4C

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
8
Biotypes
4
Peaks
258,173
Non-redundant peaks
144,673

TF Classification

Familly
NA
Sub Familly
NA

Source JASPAR

External IDs

NCBI Gene
76804
Official Gene Name
Kdm4c
JASPAR
MGI
MGI:1924054
Ensembl
ENSMUSG00000028397
UniProt
Q8VCD7
Genevisible
Q8VCD7
RefSeq
NM_144787
Aliases
2410141F18Rik; Jmjd2c
All peaks KDM4C
Download BED file
Non redundant peaks KDM4C
Download BED file
SEQUENCES KDM4C
Download FASTA file
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Datasets Table for KDM4C

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
KDM4C mESC OHT GEO Mus musculus GSE53936 561
KDM4C mESC GEO Mus musculus GSE53936 20,384
KDM4C mESC GEO Mus musculus GSE43229 61,608
KDM4C mESC-E14 2i GEO Mus musculus GSE93721 23,100
KDM4C mESC-E14 GEO Mus musculus GSE93721 53,961
KDM4C MLL-AF9 OHT GEO Mus musculus GSE81299 45,832
KDM4C MEF GEO Mus musculus GSE53939 11,183
KDM4C MLL-AF9 ctrl GEO Mus musculus GSE81299 41,544
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks