KDM5B

Information KDM5B

Description

This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]

Full Name

lysine demethylase 5B

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
9
Biotypes
8
Peaks
333,289
Non-redundant peaks
182,190

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
10765
Official Gene Name
KDM5B
JASPAR
Ensembl
ENSG00000117139
UniProt
Q9UGL1
Genevisible
Q9UGL1
RefSeq
NM_001314042
Aliases
CT31; JARID1B; MRT65; PLU-1; PLU1; PPP1R98; PUT1; RBBP2H1A; RBP2-H1
All peaks KDM5B
Download BED file
Non redundant peaks KDM5B
Download BED file
SEQUENCES KDM5B
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for KDM5B

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
KDM5B MCF-7 GEO Homo sapiens GSE46055 21,528
KDM5B SUM159 GEO Homo sapiens GSE46055 46,144
KDM5B SUM185 SHCTCF GEO Homo sapiens GSE46055 55,642
KDM5B SUM185 GEO Homo sapiens GSE46055 16,029
KDM5B T-47D GEO Homo sapiens GSE46055 54,017
KDM5B Hep-G2 ENCODE Homo sapiens ENCSR227MRE 46,670
KDM5B WA01 ENCODE Homo sapiens ENCSR000AUR 1,826
KDM5B K-562 ENCODE Homo sapiens ENCSR000AQA 31,625
KDM5B HCC2157 GEO Homo sapiens GSE46055 59,808
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks