KLF1

Information KLF1

Description

This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009]

Full Name

Kruppel like factor 1

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
6
Biotypes
4
Peaks
136,993
Non-redundant peaks
86,964

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
10661
Official Gene Name
KLF1
JASPAR
Ensembl
ENSG00000105610
UniProt
Q13351
Genevisible
Q13351
RefSeq
NM_006563
Aliases
EKLF; EKLF/KLF1
All peaks KLF1
Download BED file
Non redundant peaks KLF1
Download BED file
SEQUENCES KLF1
Download FASTA file
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Datasets Table for KLF1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
KLF1 HEK293 GEO Homo sapiens GSE76494 25,215
KLF1 erythroid R3R4 GEO Homo sapiens GSE43625 34,995
KLF1 HUDEP-2 S4 GEO Homo sapiens GSE97671 10,992
KLF1 HUDEP-2 S2 GEO Homo sapiens GSE97671 8,490
KLF1 K-562 ENCODE Homo sapiens ENCSR550HCT 9,869
KLF1 HEK293 ENCODE Homo sapiens ENCSR859BMR 47,432
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks