KLF7

Information KLF7

Description

The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Full Name

Kruppel like factor 7

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
2
Biotypes
1
Peaks
11,567
Non-redundant peaks
11,120

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
8609
Official Gene Name
KLF7
JASPAR
Ensembl
ENSG00000118263
UniProt
O75840
Genevisible
O75840
RefSeq
NM_001270942
Aliases
UKLF
All peaks KLF7
Download BED file
Non redundant peaks KLF7
Download BED file
SEQUENCES KLF7
Download FASTA file
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Datasets Table for KLF7

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
KLF7 HEK293 GEO Homo sapiens GSE76494 581
KLF7 HEK293 ENCODE Homo sapiens ENCSR604VWJ 10,986
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks