KMT2D

Information KMT2D

Description

Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription. {ECO:0000250|UniProtKB:O14686}.(Source UnitProtKB).

Full Name

lysine (K)-specific methyltransferase 2D

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
35
Biotypes
8
Peaks
937,691
Non-redundant peaks
293,477

TF Classification

Familly
NA
Sub Familly
NA

Source JASPAR

External IDs

NCBI Gene
381022
Official Gene Name
Kmt2d
JASPAR
MGI
MGI:2682319
Ensembl
ENSMUSG00000048154
UniProt
Q6PDK2
Genevisible
Q6PDK2
RefSeq
NM_001033276
Aliases
C430014K11Rik; Mll2; Mll4

External links
All peaks KMT2D
Download BED file
Non redundant peaks KMT2D
Download BED file
SEQUENCES KMT2D
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for KMT2D

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
KMT2D CD4 GEO Mus musculus GSE69162 15,109
KMT2D HT22 GEO Mus musculus GSE126166 3,614
KMT2D preadipocyte GFP GEO Mus musculus GSE50465 9,213
KMT2D pancreas GEO Mus musculus GSE104739 151
KMT2D pancreas KDM6A-KO GEO Mus musculus GSE104739 2,913
KMT2D mESC mCXXC GEO Mus musculus GSE78708 8,129
KMT2D mESC MLL4-DNT GEO Mus musculus GSE99022 33,306
KMT2D mESC KO GEO Mus musculus GSE78708 25,069
KMT2D mESC MLL4-KO GEO Mus musculus GSE99022 16,929
KMT2D mESC MLL4-DSET GEO Mus musculus GSE99022 17,779
KMT2D mESC KMT2D-f-f_EBs GEO Mus musculus GSE50534 62,854
KMT2D mESC shMEN1 GEO Mus musculus GSE78708 7,811
KMT2D mESC KMT2D-f-f GEO Mus musculus GSE50534 1,591
KMT2D mESC WT-MLL4 GEO Mus musculus GSE99022 49,060
KMT2D mESC GEO Mus musculus GSE78708 36,803
KMT2D mESC KO_vector GEO Mus musculus GSE78708 8,879
KMT2D mESC Y2602A GEO Mus musculus GSE78708 16,481
KMT2D mESC WT GEO Mus musculus GSE98140 74,477
KMT2D mESC halo_vector GEO Mus musculus GSE78708 924
KMT2D mESC KO_halo GEO Mus musculus GSE78708 4,409
KMT2D mESC halo GEO Mus musculus GSE78708 13,450
KMT2D brown-preadipocyte d7 GEO Mus musculus GSE50209 74,580
KMT2D brown-preadipocyte d7_KO GEO Mus musculus GSE50209 51,191
KMT2D brown-preadipocyte d2_KO GEO Mus musculus GSE50209 70,312
KMT2D brown-preadipocyte K27R_4OHT GEO Mus musculus GSE130091 32,247
KMT2D brown-preadipocyte GEO Mus musculus GSE130091 56,145
KMT2D brown-preadipocyte 4OHT GEO Mus musculus GSE130091 49,974
KMT2D 3T3-L1 GEO Mus musculus GSE74189 10,492
KMT2D brown-preadipocyte vec_4OHT GEO Mus musculus GSE130091 43,296
KMT2D brown-preadipocyte d0_KO GEO Mus musculus GSE50209 33,297
KMT2D bone-marrow HMM GEO Mus musculus GSE103446 380
KMT2D bone-marrow inactivation GEO Mus musculus GSE103446 1,161
KMT2D mESC KO_Y2602A GEO Mus musculus GSE78708 20,679
KMT2D mESC shGFP GEO Mus musculus GSE78708 13,563
KMT2D mESC EBs GEO Mus musculus GSE50534 53,929
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks