LDB1
Information LDB1
- Description
Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state. {ECO:0000269|PubMed:12150931, ECO:0000269|PubMed:16815859, ECO:0000269|PubMed:8876198, ECO:0000269|PubMed:8918878, ECO:0000269|PubMed:9192866, ECO:0000269|PubMed:9315627, ECO:0000269|PubMed:9391090}.(Source UnitProtKB).
- Full Name
LIM domain binding 1
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 6
- Biotypes
- 5
- Peaks
- 43,059
- Non-redundant peaks
- 39,461
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 16825
- Official Gene Name
- Ldb1
- JASPAR
- MGI
- MGI:894762
- Ensembl
- ENSMUSG00000025223
- UniProt
- P70662
- Genevisible
- P70662
- RefSeq
- NM_010697
- Aliases
- CLIM2; NLI
Datasets Table for LDB1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| LDB1 | mESC | GEO | Mus musculus | GSE126362 | 4,649 | |||
| LDB1 | EBs | GEO | Mus musculus | GSE43041 | 14,654 | |||
| LDB1 | AtT-20 | GEO | Mus musculus | GSE64483 | 12,396 | |||
| LDB1 | hemogenic-endothelium | Dox | GEO | Mus musculus | GSE104045 | 6,454 | ||
| LDB1 | hemogenic-endothelium | GEO | Mus musculus | GSE104045 | 3,029 | |||
| LDB1 | pancreas | GEO | Mus musculus | GSE84759 | 1,877 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |