LHX3
Information LHX3
- Description
Required for the establishment of the specialized cells of the pituitary gland and the nervous system (By similarity). Involved in the development of interneurons and motor neurons in cooperation with LDB1 and ISL1. Acts as a transcriptional activator. Binds to and activates the promoter of the alpha-glycoprotein gene, and synergistically enhances transcription from the prolactin promoter in cooperation with Pou1f1/Pit-1. {ECO:0000250, ECO:0000269|PubMed:10593900, ECO:0000269|PubMed:12150931}.(Source UnitProtKB).
- Full Name
LIM homeobox protein 3
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 12
- Biotypes
- 1
- Peaks
- 259,873
- Non-redundant peaks
- 94,177
TF Classification
- Familly
- Homeo domain factors
- Sub Familly
- HD-LIM factors
Source JASPAR
External IDs
- NCBI Gene
- 16871
- Official Gene Name
- Lhx3
- JASPAR
- MA0135.1
- MGI
- MGI:102673
- Ensembl
- ENSMUSG00000026934
- UniProt
- P50481
- Genevisible
- P50481
- RefSeq
- NM_010711
- Aliases
- Lim3; P-LIM; mLIM3; mLim-3
Datasets Table for LHX3
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| LHX3 | EBs | Dox-24h_iNgn2-Isl1-Lhx3-V5 | GEO | Mus musculus | GSE80321 | 77,244 | ||
| LHX3 | EBs | Dox-48h_iNgn2-Isl1-Lhx3-V5 | GEO | Mus musculus | GSE80321 | 35,739 | ||
| LHX3 | EBs | Dox-24h_Isl1-Lhx3-V5-Ebf2-Onecut2 | GEO | Mus musculus | GSE80321 | 16,015 | ||
| LHX3 | EBs | Dox-8h_iNgn2-Isl1-Lhx3-V5 | GEO | Mus musculus | GSE80321 | 39,155 | ||
| LHX3 | EBs | Dox-12h_iNgn2-Isl1-Lhx3-V5 | GEO | Mus musculus | GSE80321 | 31,456 | ||
| LHX3 | EBs | Dox-36h_Isl1-Lhx3-V5-Ebf2-Onecut2 | GEO | Mus musculus | GSE80321 | 21,283 | ||
| LHX3 | EBs | Dox-48h_iIsl1-Lhx3-V5 | GEO | Mus musculus | GSE80321 | 238 | ||
| LHX3 | EBs | Dox-12h_iIsl1-Lhx3-V5 | GEO | Mus musculus | GSE80321 | 6,251 | ||
| LHX3 | EBs | Dox-12h_Isl1-Lhx3-V5-Ebf2-Onecut2 | GEO | Mus musculus | GSE80321 | 8,606 | ||
| LHX3 | EBs | Dox-24h_iNgn2-Isl1-Lhx3-V5-Ebf2-Onecut2 | GEO | Mus musculus | GSE80321 | 21,676 | ||
| LHX3 | EBs | Dox-12h_iNgn2-Isl1-Lhx3-V5-Ebf2-Onecut2 | GEO | Mus musculus | GSE80321 | 18,618 | ||
| LHX3 | EBs | Dox-48h_Isl1-Lhx3-V5-Ebf2-Onecut2 | GEO | Mus musculus | GSE80321 | 6,929 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |