LMO2
Information LMO2
- Description
LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Nov 2008]
- Full Name
LIM domain only 2
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 7
- Biotypes
- 4
- Peaks
- 161,486
- Non-redundant peaks
- 122,352
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 4005
- Official Gene Name
- LMO2
- JASPAR
- Ensembl
- ENSG00000135363
- UniProt
- P25791
- Genevisible
- P25791
- RefSeq
- NM_001142315
- Aliases
- LMO-2; RBTN2; RBTNL1; RHOM2; TTG2
Datasets Table for LMO2
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| LMO2 | TSU-1621MT | GEO | Homo sapiens | GSE60477 | 32,043 | |||
| LMO2 | CCRF-CEM | GEO | Homo sapiens | GSE33850 | 64,084 | |||
| LMO2 | Kasumi-1 | GEO | Homo sapiens | GSE43834 | 6,524 | |||
| LMO2 | Kasumi-1 | SIRUNX1ETO | GEO | Homo sapiens | GSE60130 | 23,372 | ||
| LMO2 | Kasumi-1 | SICTR | GEO | Homo sapiens | GSE60130 | 33,020 | ||
| LMO2 | H9 | DOX-5 | GEO | Homo sapiens | GSE137670 | 1,287 | ||
| LMO2 | H9 | DOX-0 | GEO | Homo sapiens | GSE137670 | 1,156 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |