LRRFIP1
Information LRRFIP1
- Description
Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA (By similarity). Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding (By similarity). {ECO:0000250}.(Source UnitProtKB).
- Full Name
leucine rich repeat (in FLII) interacting protein 1
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 122
- Non-redundant peaks
- 122
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 16978
- Official Gene Name
- Lrrfip1
- JASPAR
- MGI
- MGI:1342770
- Ensembl
- ENSMUSG00000026305
- UniProt
- Q3UZ39
- Genevisible
- Q3UZ39
- RefSeq
- NM_008515
- Aliases
- AU024550; FLAP (FLI LRR associated protein); Fliiap1