MAFF

Information MAFF

Description

Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2L1/NRF1, and recruiting them to specific DNA-binding sites. Interacts with the upstream promoter region of the oxytocin receptor gene. May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition. {ECO:0000250|UniProtKB:Q9ULX9}.(Source UnitProtKB).

Full Name

v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
5
Biotypes
2
Peaks
20,280
Non-redundant peaks
9,797

TF Classification

Familly
NA
Sub Familly
NA

Source JASPAR

External IDs

NCBI Gene
17133
Official Gene Name
Maff
JASPAR
MGI
MGI:96910
Ensembl
ENSMUSG00000042622
UniProt
O54791
Genevisible
O54791
RefSeq
NM_010755
Aliases
All peaks MAFF
Download BED file
Non redundant peaks MAFF
Download BED file
SEQUENCES MAFF
Download FASTA file
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Datasets Table for MAFF

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
MAFF BMDC 2h GEO Mus musculus GSE36099 2,923
MAFF BMDC 30min GEO Mus musculus GSE36099 3,699
MAFF BMDC 1h GEO Mus musculus GSE36099 4,852
MAFF TSC GEO Mus musculus GSE110950 4,356
MAFF BMDC GEO Mus musculus GSE36099 4,450
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks