MAFG

Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves (PubMed:16738329, PubMed:9679061). However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2, NFE2L1 and NFE2L2, and recruiting them to specific DNA-binding sites (PubMed:16738329, PubMed:9679061). Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NFE2L2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NFE2L2. Activates globin gene expression when associated with NFE2L2 (By similarity). May be involved in signal transduction of extracellular H(+) (By similarity). {ECO:0000250|UniProtKB:O15525, ECO:0000250|UniProtKB:Q76MX4}.(Source UnitProtKB).

v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)

Source UniprotKB

Mus musculus [tax_id: 10090]

mm10