MAFK
Information MAFK
- Description
Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves (By similarity). However, they act as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2, NFE2L1/NRF1, NFE2L2/NRF2 and NFE2L3/NRF3, and recruiting them to specific DNA-binding sites (PubMed:9240432). Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor (By similarity). {ECO:0000250|UniProtKB:O60675, ECO:0000269|PubMed:9240432}.(Source UnitProtKB).
- Full Name
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 10
- Biotypes
- 7
- Peaks
- 190,041
- Non-redundant peaks
- 109,462
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
Datasets Table for MAFK
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| MAFK | MEL | dimethyl-sulfoxide_2-percent_5-day | ENCODE | Mus musculus | ENCSR000ESY | 1,968 | ||
| MAFK | M1 | GEO | Mus musculus | GSE79138 | 949 | |||
| MAFK | MEF | NIH3T3 | GEO | Mus musculus | GSE113145 | 16,930 | ||
| MAFK | MEF | GEO | Mus musculus | GSE113145 | 23,147 | |||
| MAFK | pre-pro-B-cell | GEO | Mus musculus | GSE87503 | 36,177 | |||
| MAFK | TSC | differentiated | GEO | Mus musculus | GSE110950 | 66,219 | ||
| MAFK | MEL | ENCODE | Mus musculus | ENCSR000ETK | 4,518 | |||
| MAFK | TSC | GEO | Mus musculus | GSE110950 | 3,130 | |||
| MAFK | CH12-LX | ENCODE | Mus musculus | ENCSR000ERB | 7,779 | |||
| MAFK | ES-E14 | ENCODE | Mus musculus | ENCSR604XDL | 29,224 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |