MBD4
Information MBD4
- Description
Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein. {ECO:0000269|PubMed:9774669}.
- Full Name
methyl-CpG binding domain protein 4
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 3
- Biotypes
- 2
- Peaks
- 11,511
- Non-redundant peaks
- 11,424
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 17193
- Official Gene Name
- Mbd4
- JASPAR
- MGI
- MGI:1333850
- Ensembl
- ENSMUSG00000030322
- UniProt
- Q9Z2D7
- Genevisible
- Q9Z2D7
- RefSeq
- NM_010774
- Aliases
- Med1
Datasets Table for MBD4
Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
---|---|---|---|---|---|---|---|---|
MBD4 | NPC | GEO | Mus musculus | GSE39610 | 198 | |||
MBD4 | mESC | GEO | Mus musculus | GSE39610 | 11,197 | |||
MBD4 | mESC | triple-KO | GEO | Mus musculus | GSE39610 | 116 | ||
Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |