MED12

Information MED12

Description

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway (By similarity). {ECO:0000250}.(Source UnitProtKB).

Full Name

mediator complex subunit 12

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
15
Biotypes
5
Peaks
117,895
Non-redundant peaks
68,967

TF Classification

Familly
NA
Sub Familly
NA

Source JASPAR

External IDs

NCBI Gene
59024
Official Gene Name
Med12
JASPAR
MGI
MGI:1926212
Ensembl
ENSMUSG00000079487
UniProt
A2AGH6
Genevisible
A2AGH6
RefSeq
Aliases
Mopa; OPA-1; Tnrc11; Trap230
All peaks MED12
Download BED file
Non redundant peaks MED12
Download BED file
SEQUENCES MED12
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for MED12

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
MED12 HPC-7 GEO Mus musculus GSE76053 262
MED12 MEF GEO Mus musculus GSE22562 2,890
MED12 sperm GEO Mus musculus GSE116855 6,480
MED12 mESC siEsrrb GEO Mus musculus GSE115340 17,677
MED12 mESC DKO GEO Mus musculus GSE74055 808
MED12 mESC D2_DKO GEO Mus musculus GSE74055 3,147
MED12 mESC GEO Mus musculus GSE74055 1,230
MED12 mESC GEO Mus musculus GSE80049 1,767
MED12 mESC D1_DKO GEO Mus musculus GSE74055 8,300
MED12 mESC D0_DKO GEO Mus musculus GSE74055 6,888
MED12 TSC GEO Mus musculus GSE110950 5,541
MED12 mESC GEO Mus musculus GSE59378 1,258
MED12 mESC GEO Mus musculus GSE22562 2,192
MED12 mESC D1-5_DKO GEO Mus musculus GSE74055 14,260
MED12 mESC siCtrl GEO Mus musculus GSE115340 45,195
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks