MED12
Information MED12
- Description
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway (By similarity). {ECO:0000250}.(Source UnitProtKB).
- Full Name
mediator complex subunit 12
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 15
- Biotypes
- 5
- Peaks
- 117,895
- Non-redundant peaks
- 68,967
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 59024
- Official Gene Name
- Med12
- JASPAR
- MGI
- MGI:1926212
- Ensembl
- ENSMUSG00000079487
- UniProt
- A2AGH6
- Genevisible
- A2AGH6
- RefSeq
- Aliases
- Mopa; OPA-1; Tnrc11; Trap230
Datasets Table for MED12
Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
---|---|---|---|---|---|---|---|---|
MED12 | HPC-7 | GEO | Mus musculus | GSE76053 | 262 | |||
MED12 | MEF | GEO | Mus musculus | GSE22562 | 2,890 | |||
MED12 | sperm | GEO | Mus musculus | GSE116855 | 6,480 | |||
MED12 | mESC | siEsrrb | GEO | Mus musculus | GSE115340 | 17,677 | ||
MED12 | mESC | DKO | GEO | Mus musculus | GSE74055 | 808 | ||
MED12 | mESC | D2_DKO | GEO | Mus musculus | GSE74055 | 3,147 | ||
MED12 | mESC | GEO | Mus musculus | GSE74055 | 1,230 | |||
MED12 | mESC | GEO | Mus musculus | GSE80049 | 1,767 | |||
MED12 | mESC | D1_DKO | GEO | Mus musculus | GSE74055 | 8,300 | ||
MED12 | mESC | D0_DKO | GEO | Mus musculus | GSE74055 | 6,888 | ||
MED12 | TSC | GEO | Mus musculus | GSE110950 | 5,541 | |||
MED12 | mESC | GEO | Mus musculus | GSE59378 | 1,258 | |||
MED12 | mESC | GEO | Mus musculus | GSE22562 | 2,192 | |||
MED12 | mESC | D1-5_DKO | GEO | Mus musculus | GSE74055 | 14,260 | ||
MED12 | mESC | siCtrl | GEO | Mus musculus | GSE115340 | 45,195 | ||
Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |