MED23
Information MED23
- Description
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors (By similarity). Also required for transcriptional activation subsequent to the assembly of the pre-initiation complex. Required for transcriptional activation by adenovirus E1A protein. Required for ELK1-dependent transcriptional activation in response to activated Ras signaling. {ECO:0000250, ECO:0000269|PubMed:11934987, ECO:0000269|PubMed:14759369, ECO:0000269|PubMed:15542641, ECO:0000269|PubMed:15749018}.
- Full Name
mediator complex subunit 23
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 3
- Biotypes
- 2
- Peaks
- 6,299
- Non-redundant peaks
- 6,265
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 70208
- Official Gene Name
- Med23
- JASPAR
- MGI
- MGI:1917458
- Ensembl
- ENSMUSG00000019984
- UniProt
- Q80YQ2
- Genevisible
- Q80YQ2
- RefSeq
- NM_027347
- Aliases
- 3000002A17Rik; Crsp3; ESTM7; Sur2; X83317
Datasets Table for MED23
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| MED23 | cortical-neuron | Reelin | GEO | Mus musculus | GSE66701 | 284 | ||
| MED23 | mESC | DKO | GEO | Mus musculus | GSE74055 | 164 | ||
| MED23 | mESC | GEO | Mus musculus | GSE74055 | 5,851 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |