MED26

Information MED26

Description

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq, Jul 2008]

Full Name

mediator complex subunit 26

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
5
Biotypes
3
Peaks
141,574
Non-redundant peaks
95,741

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
9441
Official Gene Name
MED26
JASPAR
Ensembl
ENSG00000105085
UniProt
O95402
Genevisible
O95402
RefSeq
NM_004831
Aliases
CRSP7; CRSP70
All peaks MED26
Download BED file
Non redundant peaks MED26
Download BED file
SEQUENCES MED26
Download FASTA file
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Datasets Table for MED26

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
MED26 HEK293T GEO Homo sapiens GSE121024 56,219
MED26 U2OS SHEP400 GEO Homo sapiens GSE73742 18,347
MED26 U2OS SHCTR GEO Homo sapiens GSE73742 23,704
MED26 HCT-116 aux GEO Homo sapiens GSE121355 23,355
MED26 HCT-116 GEO Homo sapiens GSE121355 19,949
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks