MED
Information MED
- Description
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.
- Full Name
Targetting subunits of Mediator of RNA polymerase II transcription
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 29,825
- Non-redundant peaks
- 29,825
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- JASPAR
- Ensembl
- UniProt
- Q93074
- Genevisible
- Q93074
- RefSeq
- Aliases
- ARC100; ARC150; ARC240; CAGH45; CRSP1; CRSP2; CRSP200; CRSP4; CXorf4; DRIP100; DRIP150; DRIP205; DRIP230; EXLM1; HOPA; KIAA0130; KIAA0192; KIAA1025; MED12; PBP; PPARBP; PPARGBP; PROSIT240; RB18A; RC205; RGR1; THRAP2; THRAP4; TNRC11; TRAP100; TRAP170; TRAP220; TRAP230; TRAP240L; TRIP2