MEF2A

Description: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter (By similarity). {ECO:0000250}.(Source UnitProtKB).
Full Name: myocyte enhancer factor 2A; Source UniprotKB
Species: Mus musculus [tax_id: 10090]
Genome: mm10

All peaks MEF2A

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Non redundant peaks MEF2A

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SEQUENCES MEF2A

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Got to catalogue

Target name	Target modification	Ecotype/Strain	Biotype	Biotype modification	Source	Species	Experiment	Peaks
MEF2A			CH12-LX		ENCODE	Mus musculus	ENCSR806JZK	18,039
MEF2A			MEL		ENCODE	Mus musculus	ENCSR867SDZ	3,007
MEF2A			cortical-neuron		GEO	Mus musculus	GSE66701	79,563
MEF2A			cortical-neuron	Reelin	GEO	Mus musculus	GSE66701	69,086
MEF2A			C2C12	pep1-blocked	GEO	Mus musculus	GSE43223	33,882
MEF2A			C2C12	pep2-blocked	GEO	Mus musculus	GSE43223	6,048
MEF2A			C2C12	pep2	GEO	Mus musculus	GSE43223	50,127
MEF2A			cerebellum	MEF2A-KO_Male	GEO	Mus musculus	GSE138028	361
MEF2A			HL-1		GEO	Mus musculus	GSE21529	749
MEF2A			cerebellum	MEF2D-KO	GEO	Mus musculus	GSE138028	395
MEF2A			prefrontal-cortex		GEO	Mus musculus	GSE123652	43,957
Target name	Target modification	Ecotype/Strain	Biotype	Biotype modification	Source	Species	Experiment	Peaks