MEF2D
Information MEF2D
- Description
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis. {ECO:0000269|PubMed:16407541, ECO:0000269|PubMed:18299387}.(Source UnitProtKB).
- Full Name
myocyte enhancer factor 2D
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 5
- Biotypes
- 2
- Peaks
- 28,442
- Non-redundant peaks
- 20,966
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
Datasets Table for MEF2D
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| MEF2D | cerebellum | GEO | Mus musculus | GSE138028 | 934 | |||
| MEF2D | cerebellum | MEF2A-KO | GEO | Mus musculus | GSE138028 | 1,346 | ||
| MEF2D | retina | MEF2D-KO | GEO | Mus musculus | GSE61391 | 5,777 | ||
| MEF2D | retina | Crx-KO | GEO | Mus musculus | GSE61391 | 5,391 | ||
| MEF2D | retina | GEO | Mus musculus | GSE61391 | 14,994 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |