MEIS1

Information MEIS1

Description

Acts as a transcriptional regulator of PAX6. Also acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias. {ECO:0000269|PubMed:12183364, ECO:0000269|PubMed:15882575}.(Source UnitProtKB).

Full Name

Meis homeobox 1

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
11
Biotypes
8
Peaks
204,348
Non-redundant peaks
114,810

TF Classification

Familly
Homeo domain factors
Sub Familly
TALE-type homeo domain factors

Source JASPAR

External IDs

NCBI Gene
17268
Official Gene Name
Meis1
JASPAR
MA0498.1
MGI
MGI:104717
Ensembl
ENSMUSG00000020160
UniProt
Q60954
Genevisible
Q60954
RefSeq
NM_010789
Aliases
C530044H18Rik; Evi8
All peaks MEIS1
Download BED file
Non redundant peaks MEIS1
Download BED file
SEQUENCES MEIS1
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for MEIS1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
MEIS1 HPC-7 GEO Mus musculus GSE22178 17,846
MEIS1 myeloblast GEO Mus musculus GSE33509 672
MEIS1 hematopoietic-progenitor GEO Mus musculus GSE84328 6,673
MEIS1 myeloblastic-cell GEO Mus musculus GSE33509 672
MEIS1 embryonic-carcinoma RA-48h GEO Mus musculus GSE82314 20,208
MEIS1 embryonic-carcinoma RA-24h GEO Mus musculus GSE82314 8,842
MEIS1 bone-marrow 4OHT GEO Mus musculus GSE55287 62,806
MEIS1 TSC differentiated GEO Mus musculus GSE110950 137
MEIS1 TSC GEO Mus musculus GSE110950 8,581
MEIS1 bone-marrow EtOH GEO Mus musculus GSE55287 67,042
MEIS1 AML GEO Mus musculus GSE48679 10,869
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks