MITF
Information MITF
- Description
This transcription factor serves at a critical point between extracellular signaling and downstream targets in cell specification in early eye and neural crest development. Mutant alleles have been identified that generate distinct phenotypes. Some of these alleles are being used to model the human diseases Waardenburg syndrome IIa and Tietz syndrome. [provided by RefSeq, Jul 2008]
- Full Name
melanogenesis associated transcription factor
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 3
- Biotypes
- 1
- Peaks
- 870
- Non-redundant peaks
- 487
TF Classification
- Familly
- Basic helix-loop-helix factors (bHLH)
- Sub Familly
- bHLH-ZIP factors
Source JASPAR
External IDs
- NCBI Gene
- 17342
- Official Gene Name
- Mitf
- JASPAR
- MA0620.1
- MGI
- MGI:104554
- Ensembl
- ENSMUSG00000035158
- UniProt
- Q08874
- Genevisible
- Q08874
- RefSeq
- Aliases
- BCC2; Bhlhe32; Gsfbcc2; Vitiligo; Wh; bHLHe32; bw; mi; vit; wh
Datasets Table for MITF
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| MITF | bone-marrow | RANKL-36h | GEO | Mus musculus | GSE107294 | 246 | ||
| MITF | bone-marrow | RANKL-72h | GEO | Mus musculus | GSE107294 | 530 | ||
| MITF | bone-marrow | GEO | Mus musculus | GSE107294 | 378 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |