MORC2

Information MORC2

Description

This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in repressing transcription. The protein has been found to regulate the activity of ATP citrate lyase via specific interaction with this enzyme in the cytosol of lipogenic breast cancer cells. The protein also plays a role in lipogenesis and adipocyte differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]

Full Name

MORC family CW-type zinc finger 2

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
7
Biotypes
3
Peaks
51,872
Non-redundant peaks
41,635

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
22880
Official Gene Name
MORC2
JASPAR
Ensembl
ENSG00000133422
UniProt
Q9Y6X9
Genevisible
Q9Y6X9
RefSeq
NM_001303256
Aliases
AC004542.C22.1; CMT2Z; KIAA0852; ZCW3; ZCWCC1
All peaks MORC2
Download BED file
Non redundant peaks MORC2
Download BED file
SEQUENCES MORC2
Download FASTA file
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Datasets Table for MORC2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
MORC2 HeLa V5-HUSH-KO GEO Homo sapiens GSE95451 15,545
MORC2 HeLa V5-MORC2-KO GEO Homo sapiens GSE95451 5,679
MORC2 HeLa V5-MORC2-KO-W505A-MORC2-mut GEO Homo sapiens GSE95451 12,365
MORC2 K-562 GEO Homo sapiens GSE95374 1,697
MORC2 K-562 TASOR-KO GEO Homo sapiens GSE95374 176
MORC2 K-562 MPP8-KO GEO Homo sapiens GSE95374 135
MORC2 H9 GEO Homo sapiens GSE95374 16,275
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks