MTF-1

The gene Metal response element-binding Transcription Factor-1 is referred to in FlyBase by the symbol DmelMTF-1 (CG3743, FBgn0040305). It is a protein_coding_gene from Dmel. It has 7 annotated transcripts and 7 polypeptides (4 unique). Gene sequence location is 3L:9430312..9439490. Its molecular function is described by: transcription regulatory region sequence-specific DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor activity. It is involved in the biological process described with 8 unique terms, many of which group under: response to metal ion; response to inorganic substance; response to chemical; response to stimulus; response to stress. 37 alleles are reported. The phenotypes of these alleles manifest in: mesothoracic tergum; wing. The phenotypic classes of alleles include: chemical sensitive; increased mortality; starvation stress response defective; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.

Metal response element-binding Transcription Factor-1

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6