MTF1
Information MTF1
- Description
Zinc-dependent transcriptional regulator of cellular adaption to conditions of exposure to heavy metals (PubMed:24529376). Binds to metal responsive elements (MRE) in promoters and activates the transcription of metallothionein genes like metallothionein-2/MT2A (By similarity). Also regulates the expression of metalloproteases in response to intracellular zinc and functions as a catabolic regulator of cartilages (PubMed:24529376). {ECO:0000250|UniProtKB:Q14872, ECO:0000269|PubMed:24529376}.(Source UnitProtKB).
- Full Name
metal response element binding transcription factor 1
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 145
- Non-redundant peaks
- 145
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 17764
- Official Gene Name
- Mtf1
- JASPAR
- MGI
- MGI:101786
- Ensembl
- ENSMUSG00000028890
- UniProt
- Q07243
- Genevisible
- Q07243
- RefSeq
- NM_008636
- Aliases
- MTF-1; Thyls; metal response element-binding transcription ; metalloregulatory transcription factor
Datasets Table for MTF1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| MTF1 | primary-myoblast | CuSO4-neg | GEO | Mus musculus | GSE116331 | 145 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |