MXD4

Information MXD4

Description

This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq, Jul 2008]

Full Name

MAX dimerization protein 4

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
66,467
Non-redundant peaks
66,467

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
10608
Official Gene Name
MXD4
JASPAR
Ensembl
ENSG00000123933
UniProt
Q14582
Genevisible
Q14582
RefSeq
NM_006454
Aliases
MAD4; MST149; MSTP149; bHLHc12
All peaks MXD4
Download BED file
Non redundant peaks MXD4
Download BED file
SEQUENCES MXD4
Download FASTA file
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Datasets Table for MXD4

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
MXD4 Hep-G2 ENCODE Homo sapiens ENCSR441KFW 66,467
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks