MYB

Information MYB

Description

This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Full Name

MYB proto-oncogene, transcription factor

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
15
Biotypes
11
Peaks
388,653
Non-redundant peaks
167,817

TF Classification

Super Class
Helix-turn-helix domains
Class
Tryptophan cluster factors
Familly
Myb/SANT domain factors
Sub Familly
Myb-like factors

Source TFClass

External IDs

NCBI Gene
4602
Official Gene Name
MYB
JASPAR
MA0100
Ensembl
ENSG00000118513
UniProt
P10242
Genevisible
P10242
RefSeq
NM_001130172
Aliases
Cmyb; c-myb; c-myb_CDS; efg
All peaks MYB
Download BED file
Non redundant peaks MYB
Download BED file
SEQUENCES MYB
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for MYB

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
MYB U-937 vehicle-treated_MYB GEO Homo sapiens GSE98006 1,483
MYB U-937 ATRA-treated_MYB GEO Homo sapiens GSE98006 445
MYB MV4-11 GEO Homo sapiens GSE94240 243
MYB MV4-11 TG3 GEO Homo sapiens GSE94240 256
MYB THP-1 GEO Homo sapiens GSE90769 58,307
MYB THP-1 OG86 GEO Homo sapiens GSE90769 39,366
MYB Jurkat GEO Homo sapiens GSE59657 63,309
MYB Loucy GEO Homo sapiens GSE94000 36,295
MYB SEM GEO Homo sapiens GSE117864 22,962
MYB MOLT-3 GEO Homo sapiens GSE59657 48,318
MYB GM12878 ENCODE Homo sapiens ENCSR819ATC 11,494
MYB CD4 Th1 GEO Homo sapiens GSE72266 37,165
MYB CD4 TH2 GEO Homo sapiens GSE72266 11,473
MYB PF-382 GEO Homo sapiens GSE94000 26,204
MYB DU528 GEO Homo sapiens GSE94000 31,333
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks